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Celebrex |
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- Description - |
Celebrex is prescribed for acute pain, menstrual cramps, and thepainand inflammation of osteoarthritis and rheumatoid arthritis.It is the first of a new class of nonsteroidalanti-inflammatory drugs (NSAIDs) called "COX-2 inhibitors." LikeolderNSAIDs such as Motrin and Naprosyn, Celebrex is believed to fightpainand inflammation by inhibiting the effect of a natural enzyme calledCOX-2. Unlike the older medications, however, it does not interferewitha similar substance, called COX-1, which exerts a protective effectonthe lining of the stomach. Celebrex is therefore less likely tocausethe bleeding and ulcers that sometimes accompany sustained use oftheolder NSAIDs.
Celebrex has also been found to reduce the number of colorectalpolyps(growths in the wall of the lower intestine and rectum) in peoplewho sufferfrom the condition called familial adenomatous polyposis (FAP), aninheritedtendency to develop large numbers of colorectal polyps thateventually become cancerous. |
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- Common Side Effects - |
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Abdominal pain,diarrhea,headache,indigestion,nausea,respiratory infection,sinus inflammation |
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- Possible Interactions - |
ACE-inhibitors (a type of blood pressure and heart medication,including such drugs as Capoten, Vasotec, and Prinivil)
Aspirin
Blood thinning agents such as Coumadin
Fluconazole (Diflucan)
Furosemide (Lasix)
Lithium (Eskalith, Lithobid)
Thiazide diuretics (water pills) such as hydrochlorothiazide andDyazide
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- Manufacturer - |
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Pfizer U.S. Pharmaceuticals Group |
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235 East 42nd Street |
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New York, NY 10017-5755 |
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USA |
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