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Glucovance |
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- Description - |
Glucovance is used in the treatment of type 2 (noninsulin dependent)diabetes. Diabetes develops when the body's ability to burn sugar declinesand the unused sugar builds up in the bloodstream. Ordinarily, sugar ismoved out of the blood and into the body's cells by the hormone insulin.A buildup occurs when the body either fails to make enough insulin ordoesn't respond to it properly.
Glucovance is a combination of 2 drugs--glyburide (DiaBeta, Micronase)and metformin (Glucophage)--that attack high blood sugar levels in severalways. The glyburide component stimulates the pancreas to produce moreinsulin and helps the body use it properly. The metformin component alsoencourages proper insulin utilization, and in addition works to decreasesugar production and absorption. Glucovance is prescribed when diet andexercise prove insufficient to keep sugar levels under control. |
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- Common Side Effects - |
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Cold sweats,diarrhea,dizziness,headache,hunger,nausea,shakiness,stomach pain,upper respiratory infections,vomiting |
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- Possible Interactions - |
Airway-opening drugs such as Proventil and Ventolin
Beta-blockers (heart and blood-pressure drugs such as Inderal and Tenormin)
Birth control pills
Calcium channel blockers (heart medications) such as Calan, Isoptin, and Procardia
Chloramphenicol (Chloromycetin)
Ciprofloxacin (Cipro)
Estrogens such as Premarin
HydroDiuril, Lasix, and other diuretics
Isoniazid (Rifamate)
Major tranquilizers such as Compazine, Stelazine, and Thorazine
MAO inhibitors such as the antidepressants Nardil and Parnate
Nonsteroidal anti-inflammatory drugs such as Advil, Motrin, Naprosyn, and Voltaren
Niacin (Niacor, Niaspan)
Phenytoin (Dilantin)
Probenecid
Steroids such as prednisone (Deltasone)
Sulfa drugs such as Bactrim
Thyroid medications such as Synthroid
Warfarin (Coumadin)
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- Manufacturer - |
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Bristol-Myers Squibb |
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PO Box 4500 |
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Princeton, NJ 08540-4500 |
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USA |
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