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Sandimmune |
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- Description - |
Sandimmune is given after organ transplant surgeryto help prevent rejection of organs (kidney, heart, or liver) by holding downthe body's immune system. It is also used to avoid long-term rejection inpeople previously treated with other immunosuppressant drugs,such as Imuran.
Neoral is a newer formulation of Sandimmune's active ingredient,cyclosporine. In addition to prevention of organ rejection, it isprescribed for certain severe cases of rheumatoid arthritis andpsoriasis.
Some doctors also prescribe Sandimmune to treat alopecia areata (localizedareas of hair loss), aplastic anemia (shortage of red and white blood cellsand platelets), Crohn's disease (chronic inflammation of the digestive tract),and nephropathy (kidney disease). Sandimmune is sometimes used in the treatmentof severe skin disorders, including psoriasis and dermatomyositis (inflammationof the skin and muscles causing weakness and rash). The drug is also used inprocedures involving bone marrow, the pancreas, and the lungs.
Sandimmune is always given with prednisone or a similarsteroid. It is available in capsules and liquid, or as an injection. |
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- Common Side Effects - |
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Abdominal discomfort,acne,breathing difficulty,convulsions,coughing,cramps,diarrhea,flu-like symptoms,flushing,headache,liver damage,lymph system tumor,muscle, bone, or joint pain,nasal inflammation,nausea,numbness or tingling,sinus inflammation,vomiting,wheezing |
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- Possible Interactions - |
Allopurinol (Zyloprim)
Amiodarone (Cordarone)
Amphotericin B (Fungizone, Abelcet)
Bromocriptine (Parlodel)
Calcium-blocking heart and blood pressure medications such as Calan, Cardene, Procardia, andCardizem
Carbamazepine (Tegretol)
Cimetidine (Tagamet)
Clarithromycin (Biaxin)
Colchicine
Danazol (Danocrine)
Diclofenac (Voltaren, Cataflam)
Digoxin (Lanoxin, Lanoxicaps)
Erythromycin (E.E.S., Erythrocin, others)
Fluconazole (Diflucan)
Gentamicin (Garamycin)
Indinavir (Crixivan)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Lovastatin (Mevacor)
Melphalan (Alkeran)
Methotrexate
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol)
Metoclopramide (Reglan)
Nafcillin (Unipen)
Nelfinavir
Nonsteroidal anti-inflammatory drugs such as Clinoril and Naprasyn
Octreotide (Sandostatin)
Orlistat (Xenical)
Phenobarbital
Phenytoin (Dilantin)
Potassium-sparing diuretics (Dyrenium, Midamor, Aldactone)
Prednisolone |
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- Manufacturer - |
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Novartis Pharmaceuticals |
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One Health PLaza Building 415 Room1014C |
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East Hanover, NJ 07936 |
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USA |
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