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Sinemet CR

- Description -
Sinemet CR is a controlled-release tablet that may be givento help relievethe muscle stiffness, tremor, and weakness caused by Parkinson's disease. Itmay also be given to relieve Parkinson-like symptoms caused byencephalitis(brain fever), carbon monoxide poisoning, or manganese poisoning.
Sinemet CR contains two drugs, carbidopa and levodopa. Thedrug thatactually produces the anti-Parkinson's effect is levodopa.Carbidopa preventsvitamin B6 from destroying levodopa, thus allowinglevodopa to work moreefficiently.
Parkinson's drugs such as Sinemet CR relieve the symptoms ofthe disease,but are not a permanent cure.
- Common Side Effects -
Confusion,hallucinations,nausea,uncontrollable twitching or jerking
- Possible Interactions -
Antacids such as Di-Gel, Maalox, and Mylanta
Antiseizure drugs such as Dilantin
Antispasmodic drugs such as Artane and Cogentin
Antihypertensives such as Aldomet and Clonidine
High-protein foods
Isoniazid (Nydrazid)
Major tranquilizers such as Haldol, Mellaril, Risperdal, andThorazine
MAO inhibitors such asthe antidepressants Nardil and Parnate and the Parkinson's drug Eldepryl
Methionine drugs such as Pedameth
Metoclopramide (Reglan)
Papaverine (Pavabid)
Pyridoxine (Vitamin B6)
Tranquilizers such as Dalmane, Valium, and Xanax
Tricyclic antidepressants such as Elavil andTofranil
If you have been taking an MAO inhibitorsuch as Nardil or Parnate, you must discontinue it at least 2 weeks beforestarting to take Sinemet CR.
A high-protein diet may impair the effectiveness of Sinement CR.Iron supplements can also reduce its effect.
- Manufacturer -
Bristol-Myers Squibb Medical Imaging
331 Treble Cove Road
Billerica, MA 01862
USA
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